Support Mucosa™
Protection and restoration of the intestinal
mucosal lining, your first-line immune
defense
Your
First-Line Immune Defense | Nourish
and Restore
The Formula | References
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- Nourishes the intestinal lining which
is coated with a protective barrier,
strengthening this first line of immune
defense
- Helps protect the body against harmful
organisms found in the gut
- Reduces gut inflammation
- Alleviates gastrointestinal discomfort
- Improves nutrient absorption
- Reverses the damage caused by food
intolerances, parasitic infections,
inflammatory bowel disease, Crohn’s
disease, colitis and leaky gut syndrome
- Reduces the burden on the liver from
toxins leaking through the gut wall
†
Your
First-Line Immune Defense
The mucosal barrier—your first-line
immune defense—refers to all
of the mucous membranes that comprise
the primary interface between the external
environment and the internal environment
of the body. Support Mucosa targets the
most critical barrier, that which lines
your intestines. This mucosal barrier
lets beneficial things into your general
circulation and keeps harmful ones out.
To clarify this, an analogy can be made
between the earth’s ozone layer
and your body’s mucosal barriers.
The ozone layer lets the right amount
of sunlight through, sustaining life on
earth; your mucosal barriers allow nutrients
through, sustaining your health. The ozone
layer prevents harmful radiation from
getting through; the mucosal barriers
prevent infectious agents and allergens
from invading your body. But just as our
planet has a damaged ozone layer, many
of us have damaged mucosal barriers. Consequently,
we are not protected from harmful substances
such as parasites, viruses, and bacteria.
No disease or symptom needs to be present
to warrant protecting the mucosal barrier
of the intestines; keeping it healthy
helps to keep us strong and disease-resistant.
Strengthening the gut lining is applicable
to relieving and avoiding the impacts
of asthma, arthritis, food allergies,
ulcers, Crohn’s, ulcerative colitis,
celiac disease, autoimmune diseases, alcoholism,
chronic fatigue, joint pain, migraines,
diarrhea, parasitic infections, dysbiosis,
candidiasis, multiple sclerosis, and diabetes,
all of which can have their origin in
harmful substances entering the body from
the intestines.
Inflammation—commonly caused by
food intolerances and infections—damages
these tissues. This image illustrates
the shape and components of a healthy
mucosal barrier.

In the image below, we see a healthy
mucosal lining (left) and one with collapsed
tissues—caused by inflammation—on
the right. When the finger-like projections
called villi collapse visible
on the right—harmful organisms are
harbored and given a safe place to thrive,
while nutrient absorption becomes compromised.
The promotion of healing and protection
against such damage is paramount to overall
health and disease prevention.

Nourish
and Restore
Healing of the mucosal barrier can occur
when the causes of inflammation are removed
and targeted nutrition is delivered. Support
Mucosa is specifically formulated to accelerate
repair of the mucosal barrier of the gut
wall, restoring healthy form and function
to damaged tissue. It reduces overall
inflammation and supports the liver by
preventing toxins from leaking through
and damaging this organ, while soothing
and restoring the intestinal lining.
A principal component in the formula
is the amino acid Glutamine. Glutamine’s
ability to heal the mucosal barrier cells
and tissue is well known in nutritional
science, as is its role in reducing the
amount of toxins that penetrate through
the barrier into the bloodstream. Glutamine
is arguably the most important amino acid
given its ability to rebuild tissues and
strengthen immune function.
Dr. Timmins’ First-Line™
Proprietary Blend is a synergistic mix
of botanicals that reduces gut inflammation
and assists in tissue repair. Combined
with the soothing and restorative ingredients
quercetin, MSM, bromelain, gamma oryzanol,
and N-Acetyl-D-Glucosamine, an amino acid
sugar essential for tissue repair, First-Line™
acts as a cohesive healing force. It can
improve mucosal barrier integrity, contributing
to improved nutrient absorption and protection
against foreign agents.
Like each of the BioMatrix formulas,
Support Mucosa’s formulation is
the result of Dr. Timmins’ experience
with virtually every major line of nutrition
product available and his appreciation
for the subtle interactions between botanicals.
And given the array of ingredients, each
with diverse contributions to health,
its benefits extend far beyond the primary
purpose of healing and strengthening the
intestinal wall.
Support
Mucosa - The Formula
3 Capsules Contain:
- Biotin - 1000 mcg
- Biotin enters the body through the
intestinal mucosa. When a mucosal
lining is compromised, supplemental
biotin helps to maintain therapeutic
levels in circulation. Apart from
being a vital cofactor to several
enzymes responsible for reducing inflammation,
biotin is essential in cell growth
through its role in the manufacture
of DNA and RNA, the genetic components
of cells. REF
1, 2
- L-Glutamine USP - 425 mg
- Glutamine plays a key role in the
metabolism, structure, and function
of the entire gastrointestinal tract,
and its extensive immune system. It
is the preferred respiratory fuel
for cells called enterocytes and colonocytes.
Maintaining the biological activity
of these cells is fundamental to maintaining
the integrity of the intestinal barrier.
In addition, glutamine helps maintain
secretory IgA, the antibody that prevents
the attachment of foreign substances
to mucosal cells. REF
3, 4,
5, 6
- Quercetin - 340 mg
- Found in only a few dietary sources,
quercetin is an antioxidant flavonoid
well known for suppressing asthma
symptoms. Quercetin prevents the
formation of certain inflammatory
mediators, thus reducing inflammation
and pain in many instances. The
mechanism is similar to that of
aspirin, but without the side effects.
Quercetin also spares vitamin C
and stabilizes cell membranes, including
those of the mast cells critical
to the mucosal immune function.
REF 7,
8,
9
- N-Acetyl-D-Glucosamine - 250
mg
- Acetyl-D-Glucosamine, a component
of intestinal mucous secretions, is
deficient in an inflamed bowel, thus
reducing the integrity of the mucosal
surfaces. Research shows N-Acetyl-D-Glucosamine
to be an effective component in the
treatment in inflammatory bowel disease.
REF 10,
11
- Methylsulfonylmethane (MSM)
- 160 mg
- Experiments with MSM have demonstrated
that it binds to the intestinal
mucosa. By doing so, it presents
a blocking interface between the
internal environment of the body
and the influences of the external
environment. As a result, substances
such as allergens and parasites
cannot readily bind to the mucosa,
toxins are oxidized, and free radicals
are eliminated. REF
12, 13
- Bromelain (2400 GDU/g) from
pineapple - 85 mg
- Bromelain is an anti-inflammatory
enzyme used to reduce or eliminate
pain, aid digestion, accelerate
healing, prevent strokes and reduce
blood pressure. Derived from pineapple,
its primary purpose in Support Mucosa
is the control of local inflammation.
REF 14,
15
- Gamma Oryzanol - 85 mg
- Gamma oryzanol, a component of
rice bran oil, has been shown to
reduce small bowel ulcer formation-by
inhibition of gastric acid secretion-and
have antioxidant effects on the
gastrointestinal mucosa. In one
study, gamma oryzanol shows improvement
of gastritis in over 62% of the
subjects involved.
REF 16, 17
- First-LineT Proprietary Blend
- 500 mg
- Deglycyrrhized Licorice Root
Extract
- Deglycyrrhized licorice (DGL)
increases the quantity and quality
of the natural protective substances
that line the intestinal tract
and increases the blood supply
to the intestinal lining. REF
18, 19
- Hawthorne Berry Extract
- Well known for its effectiveness
at reducing the risk of heart
disease, hawthorn berry extract
gently dilates the coronary
vessels, increasing the supply
of arterial blood to the heart.
This action enhances circulation
and oxygen utilization throughout
the mucosal tissues. REF
20,
21
- Milk Thistle Seed Extract (Standardized
to Contain 80% Silymarin)
- Milk thistle has been shown
to support healthy liver function
and decrease blood sugar levels,
both actions that contribute
to the healing process stimulated
by the formula. The extract
helps the liver manage the burden
of extra toxins permeating through
a compromised mucosal barrier.
REF
22, 23
- Eleuthero (Siberian Ginseng)
Root Extract
(Standardized to Contain 0.8% Eleutherosides)
- In studies, eleuthero appears
to boost immune system function
by increasing the activity of
immune system cells. By helping
the body to tolerate mental
and physical stress, it promotes
tissue repair and supports mucosal
immune activity. REF
24, 25
- Slippery Elm Bark
- Slippery elm bark has noted
anti-inflammatory activity and
is very rich in mucilage, a
complex mixture of polysaccharides
(complex carbohydrates). Because
the mucilage resists digestion
by stomachs acids and enzymes,
the bark exacts a soothing action
throughout the entire digestive
system. REF
26, 27
- Turmeric Root Extract (Standardized
to Contain 95% Curcumin)
- Studies indicate that the
curcumin in turmeric root has
anti-inflammatory properties
that inhibit COX-2 activity.
COX-2 is an enzyme responsible
for inflammation and pain. The
low incidence of colorectal
cancers observed in Asia is
thought to be linked to high
dietary intake of turmeric.
REF
28, 29
Other ingredients:
Natural vegetable capsules, magnesium
stearate, and microcrystalline cellulose.
Suggested Use:
- 3 capsules 2x daily 15 minutes before
meals or as directed by a health professional
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in a patient with short bowel syndrome
during home parenteral nutrition;
N Khalidi, Wesley JR, JG Thoene, Whitehouse
WM Jr, and WL Baker; Journal of Parenteral
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3, 311-314
- Biotin-mediated
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and K. Dakshinamurti; Biochem J. 1974
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- Glutamine and the
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der Hulst RR, van Kreel BK, von Meyenfeldt
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Langkamp-Henken B, Suzuki K, Stahlgren
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- Effects of glutamine
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- Dietary flavonol
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Föllmer, Siegfried Wolffram; Am J
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275: G1166-G1172, 1998; 0193-1857/98
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Repair the gastric mucosa,
epithelial lining of the intestines.
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