Support Anti-Ox™
Protection from oxidative stress with
therapeutic levels of powerful antioxidants
Oxidative
Stress and Free Radical Damage
Therapeutic Levels of Antioxidants
The Formula |
References
- Protects healthy cells from oxidative
stress
- Reduces damage caused by free radicals
- Helps reverse damage caused by chronic
stress
- Enhances energy metabolism and cellular
respiration
- Helps prevent oxidation-related damage
to hormone and immune processes

- Contributes to heart and brain health
- Helps maintain smooth and firm skin
- Highly bioavailable forms of essential
nutrients
- Therapeutic quantities of Coenzyme
Q10, Alpha-Lipoic acid, and grape seed
extract
- The quality of raw materials in BioMatrix™
Support Anti-Ox is exceptional
Oxidative Stress
and Free Radical Damage
Oxidative stress occurs when the production
of free radicals and other oxidative molecules
exceeds the capacity of the body's antioxidant
defenses. Cells react with oxygen as part
of energy metabolism. As a consequence
of these normal processes, free radicals
- atoms or molecules which have unpaired
electrons - are produced. Free radicals
are very unstable and react with other
compounds, to capture a needed electron
to gain stability. Generally, free radicals
attack the nearest stable molecule, stealing
its electron. When that molecule loses
its electron, it becomes a free radical
itself, beginning a chain reaction. Once
the process is started, it can cascade,
resulting in the disruption of healthy
cells.
Free radicals are produced normally in
the body during metabolism and also as
a result of chronic stress. Also, living
in a world that is far from clean and
pure, the body must cope with the daily
challenges of a toxic world. A strong
and effective dietary supplement can overcome
the unavoidable, harmful effects of our
environment. For patients with pronounced
oxidative stress (revealed through laboratory
markers such as lipid peroxides) higher
dosages can be used to reverse damage
and resist future problems.
Therapeutic
Levels of Antioxidants
Support Anti-Ox is a potent antioxidant
formula with a synergistic blend of nutrients
formulated to protect every cell in the
body from free radical damage. When Dr.
Timmins set out to create an antioxidant
formula for his patients, he had questions
for prominent manufacturers about their
formulas: “Why are the levels of
CoQ10 so low? Why is there such a small
amount of Alpha Lipoic acid and grape
seed extract? Why don’t you use
natural carotenoids?” To these questions
and others he received a consistent response:
“It would be too expensive. We compete
with health food stores.” Knowing
that patients with pronounced oxidative
stress require high levels of certain
nutrients, Dr. Timmins took the position
that it is costly to use cheap antioxidants
– he formulated Support Anti-Ox
to provide robust antioxidant support.
A Single Antioxidant Product: Better
Absorption and Improved Compliance
It would take multiple multi-nutrient
antioxidant products to achieve the combined
therapeutic levels available in Support
Anti-Ox. This popular product is the result
of Dr. Timmins' study of hundreds of patients
and their oxidative stress lab results.
Using the data yielded by his clinical
study, Dr. Timmins was able to synthesize
a single product that incorporates antioxidants
proven successful in fighting oxidative
stress. Besides classic free radical scavengers
and the finest antioxidant substances
in their ideal forms, Support Anti-Ox
also includes pure-form bioflavonoids,
which are necessary for tissue healing
and reducing the inflammation that is
associated with excessive oxidative stress.
Support Anti-Ox is an ideal daily supplement
also used by doctors in therapeutic protocols
that address advanced oxidative stress.
Support Anti-Ox
– The Formula
Two Capsules of Support Anti-Ox Contain:
- Vitamin A (as 10000 IU Betatene®
natural mixed carotenoids and 2000 IU
Vitamin A Palmitate) - 12,000 IU
- A free radical scavenger, vitamin
A's roles in health and physiology
are numerous. The blend of Betatene®
natural mixed carotenoids and Vitamin
A Palmitate in Support Anti-Ox is
balanced to provide easy absorption
and improved metabolism. Many patients
have a problem converting beta carotene
into vitamin A so the Vitamin A precursor
Vitamin A Palmitate is used. Betatene®
natural mixed carotenoids contain
several carotenoids derived from Dunaliella
salina algae that are broadly accepted
by the scientific community. 1,
2, 3
- Vitamin C (342 mg as Calcium
Ascorbate, 342 mg as Magnesium Ascorbate,
16 mg as Ascorbyl Palmitate) - 700 mg
- Vitamin C is another important free
radical scavenger. The 700 mg in Support
Anti-Ox is comprised of three different
forms, each serving particular metabolic
mechanisms to best support the formula's
other components. Importantly Vitamin
C combats the peroxidation of lipids,
which has been linked to degeneration
and the aging process. One study of
elderly people found that 400 mg of
vitamin C per day (for a one-year
period) reduced serum lipid peroxide
levels significantly. 4,
5
- Calcium (as Calcium Ascorbate)
- 48 mg
- The calcium portion of the Calcium
Ascorbate used primarily to provide
quality Vitamin C.
- Vitamin E (as d-alpha tocopherol
acid succinate) - 400 IU
- Another essential free radical scavenger,
vitamin E's antioxidant properties
are well known and proven. The vitamin
E in Support Anti-Ox comes in the
form of d-alpha tocopherol acid succinate
to guarantee the best possible absorption
given the formula's other ingredients.
The succinate form of vitamin E appears
to benefit areas of the tissues that
are unavailable to the other forms.
For this reason, there is a tendency
to regard alpha-tocopherol succinate
as a distinctly unique and beneficial
compound. Unlike other forms of vitamin
E, alpha-tocopherol succinate appears
to have longer half-life in the body,
and does not interfere with vitamin
A absorption. 6,
7
- Magnesium (as Magnesium Ascorbate)
- 26 mg
- The magnesium portion of the Magnesium
Ascorbate used primarily to provide
quality Vitamin C.
- Selenium (as Selenium Chelate)
- 75 mcg
- One of the most well-known and
proven antioxidants, selenium activates
the antioxidant enzyme glutathione
peroxidase. Long known as a substance
synergistic with vitamin E, it is
provided here in a chelate to ensure
optimal absorption. 8,
9
- Lemon Pure Form Bioflavonoid
Complex - 100 mg
- This bioflavonoid complex assists
vitamin C in keeping collagen healthy,
is essential for proper absorption
of vitamin C, and prevents vitamin
C from being destroyed by oxidation.
Bioflavonoids are important for
supporting vitamin C's antioxidant
properties and reversing the damage
caused by oxidation. 10,
11
- Alpha-Lipoic Acid - 100 mcg
- The body needs Alpha-Lipoic Acid
(ALA) to produce energy. It plays
a crucial role in the mitochondria,
the energy-producing structures
in cells. The body produces enough
ALA for these basic functions. This
compound acts as an antioxidant
only when there is an excess of
it (and it is in a state that is
available to the cells). There is
little free ALA circulating in the
body, unless acquired through supplementation.
Foods contain miniscule amounts
of it. ALA is a unique antioxidant
due to its versatility - it helps
deactivate an wide array of cell-damaging
free radicals in many bodily systems.
Support Anti-Ox provides therapeutic
levels to serve the goals of discerning
practitioners. 12,
13, 14
- Activin®; Dried ethanol extract
of grape seed (Vitis vinifera) - 75
mg
- Antioxidants, called oligomeric
proanthocyanidins (OPCs), found
in grape seed extract are significantly
more potent than vitamins A, C,
and E. Activin® grape seed extract
is 2.4 times more potent than vitamin
E, 4.8 times more potent than vitamin
C and 7.3 times more potent than
beta-carotene. Activin or grape
seed proanthocyanidins are sustained-release
antioxidants, remaining in the body
up to 7-10 days following ingestion.
15,
16
- Coenzyme Q10 - 50 mg
- CoQ10's key role is to produce
adenosine triphosphate (ATP), needed
for energy production in every cell
of the body, and is used readily
for cardiovascular support. Secondarily,
CoQ10 functions as a powerful antioxidant.
The antioxidant nature of CoQ10
is derived from its energy carrier
function. As an energy carrier,
the CoQ10 molecule continuously
goes through an oxidation-reduction
cycle. As it accepts electrons,
it becomes reduced. As it gives
up electrons, it becomes oxidized.
In its reduced form, the CoQ10 molecule
holds electrons rather loosely,
so this Coenzyme Q molecule will
easily give up one or both electrons
and thus act as an antioxidant.
The amount of CoQ10 in Support Anti-Ox
is sufficient to make a powerful
impact unlike most antioxidant formulas
which minimize the use of this expensive
nutrient. 17,
18, 19
- Rutin - 5 mg
- Rutin attaches to the iron ion
Fe2+, preventing it from binding
to hydrogen peroxide and creating
a highly reactive free radical.
Rutin is a natural bioflavonoid
extracted from fruits of the Fava
D'Anta tree native to Brazil. 20,
21
_____________________________________________________________
Suggested Use:
- Two capsules a day for maintenance
in the absence of elevated lipid peroxides
or other clinical indicators of oxidative
stress. Always take Support Anti-Ox
with meals.
- Individualized dosages can be further
refined with data provided by testing
lipid peroxide levels (For
more information on oxidative stress
testing).
References
- Levy. Beta-carotene
affects antioxidant status in non-insulin
dependent. Pathophysiology. 1999;6(3):157-161.
- Sies H., Stahl
W. Vitamins E and C, beta -carotene,
and other carotenoids as antioxidants.
Am. J. Clin. Nutr. 1995; 62:1315S-1321S
- Stahl W; Schwarz
W; Sies H;. Human serum concentrations
of all-trans beta- and alpha-carotene
but not 9-cis beta-carotene increase
upon ingestion of a natural isomer
mixture obtained from Dunaliella salina
(Betatene). J Nutr. 123: 847-851.
- Zan T, Tao J, Tang
RC, Liu YC, Liu Y, Huang B, Zhou JY,
Wu MH, Liu HL. Effect of vitamin C
antioxidative protection on human
red blood cells. Zhongguo Shi Yan
Xue Ye Xue Za Zhi. 2005 Dec;13(6):1106-8.
- Lehmann C, Usichenko
TI, Pavlovic D. From scurvy to sepsis:
vitamin C--A pill for all seasons?
Crit Care Med. 2005 Aug;33(8):1881-2.
- Azzi A, Breyer I,
Feher M, et al. Specific cellular
responses to a-tocopherol. J Nutr
2000;130:1649-52.
- Meydani SN, Meydani
M, Blumberg JB, Leka LS, Pedrosa M,
Diamond R, Schaefer EJ. Assessment
of the safety of supplementation with
different amounts of vitamin E in
healthy older adults. Am J Clin Nutr
1998;68:311-8.
- Rayman MP. The
importance of selenium to human health.
Lancet. 2000;356(9225):233-241.
- Hendler SS, Rorvik
DR, eds. PDR for Nutritional Supplements.
Montvale: Medical Economics Company,
Inc; 2001.
- Vinson JA, Bose
P. Comparative bioavailability to
humans of ascorbic acid alone or in
a citrus extract. Am J Clin Nutr 1988;48:601-4.
- Kuo SM. Antiproliferative
potency of structurally distinct dietary
flavonoids on human colon cancer cells.
Cancer Lett 1996;110:41-8.
- Kramer K, Packer
L. R-alpha-lipoic acid. In: Kramer
K, Hoppe P, Packer L, eds. Nutraceuticals
in Health and Disease Prevention.
New York: Marcel Dekker, Inc.; 2001:129-164.
- Packer L. alpha-Lipoic
acid: a metabolic antioxidant which
regulates NF-kappa B signal transduction
and protects against oxidative injury.
Drug Metab Rev. 1998;30(2):245-275.
- Suh JH, Shigeno
ET, Morrow JD, et al. Oxidative stress
in the aging rat heart is reversed
by dietary supplementation with (R)-(alpha)-lipoic
acid. Faseb J. 2001;15(3):700-706.
- Krohn RL, In Vitro
and In Vivo Free Radical Scavenging
Abilities of a Novel Grape Seed Proanthocyanidin
Extract and Selected Antioxidants,
The 1997 Midwest Student Medical Research
Forum XXVIII, Omaha, NE, February
21-22, 1997.
- Scheckenbach RP,
Comparative In Vitro and In Vivo Free
Radical Scavenging Abilities of Grape
Seed Proanthocyanidins and Selected
Antioxidants, International Conference
on Stress Adaptation, Prophylaxis
and Treatment, Calcutta, India, January
10-12, 1998.
- Crane FL. Biochemical
functions of coenzyme Q10. J Am Coll
Nutr. 2001;20(6):591-598.
- Mohr D, Bowry VW,
Stocker R. Dietary supplementation
with coenzyme Q10 results in increased
levels of ubiquinol-10 within circulating
lipoproteins and increased resistance
of human low-density lipoprotein to
the initiation of lipid peroxidation.
Biochim Biophys Acta. 1992;1126(3):247-254.
- Alho H, Lonnrot
K. Coenzyme Q supplementation and
longevity. In: Kagan VE, Quinn PJ,
eds. Coenzyme Q: Molecular Mechanisms
in Health and Disease. Boca Raton:
CRC Press; 2001:371-380.
- Grinberg LN, Rachmilewitz
EA, Newmark H. Protective effects
of rutin against hemoglobin oxidation.
Biochem Pharmacol. 1994 Aug 17; 48(4):
643-9.
- Webster, R.P.,
et al., Protective effect of rutin,
a flavonol glycoside, on the carcinogen-induced
DNA damage and repair enzymes in rats.
Cancer Lett. 109, 185-191, (1996).
|